The potential of enzymes for the resource-saving production of fine chemicals, pharmaceuticals, aromas and many other chemicals is not nearly exhausted yet. The DFI covers all essential steps in the development of enzyme-based processes. This includes the expansion of substrate and product spectra, the optimization of enzyme expression, the evaluation of alternative solvents (especially deep eutectic solvents), enzyme engineering and in particular the development of novel reactor concepts (electro-enzymatic and photo-enzymatic syntheses). Most of the research focusses on industrially relevant hydroxylations with peroxygenases and P450 monooxygenases.
B. O. Burek, A. W. H. Dawood, F. Hollmann, A. Liese, D. Holtmann
S. Bormann, H. Kellner, J. Hermes, R. Herzog, R. Ullrich, C. Liers, R.Ulber, M. Hofrichter, D. Holtmann
Period: 01.11.2019-31.10.2022 Funder: Deutsche Forschungsgemeinschaft (DFG) Funding code: BL 1425/1-2 Project Manager:...
Period: 01.1.2018 - 31.05.2022 Partner: Hochschule Geisenheim University Justus-Liebig-University Giessen...
L. Drummond,, C. von Wallbrunn, M. Buchhaupt
S. Jacob, S. Bormann, M. Becker, L. Antelo, D. Holtmann, E. Thines
H. T. Duong, Y. Wu, A. Sutor, B. O. Burek, F. Hollmann, J. Z. Bloh
S. Bormann, D. Hertweck, S. Schneider, J. Z. Bloh, R. Ulber, A. C. Spiess, D. Holtmann
Most industrial synthesis of fuels and chemicals are currently based on the use of fossil carbon sources such as oil, gas and coal. It has long been known...