The potential of enzymes for the resource-saving production of fine chemicals, pharmaceuticals, aromas and many other chemicals is not nearly exhausted yet. The DFI covers all essential steps in the development of enzyme-based processes. This includes the expansion of substrate and product spectra, the optimization of enzyme expression, the evaluation of alternative solvents (especially deep eutectic solvents), enzyme engineering and in particular the development of novel reactor concepts (electro-enzymatic and photo-enzymatic syntheses). Most of the research focusses on industrially relevant hydroxylations with peroxygenases and P450 monooxygenases.
Period: 01.04.2016 - 31.03.2019 Partner: Universität Wageningen (Wageningen, NL) Centre de Recerca en AgriGenomica...
M. Hümmer, S. Kara, A. Liese, I. Huth, J. Schrader, D. Holtmann
Max J. Kschowak, H. Wortmann, J. S. Dickschat, J. Schrader, M. Buchhaupt
Terpenes are the largest natural product class, for which more than 70.000 compounds are currently known. Among them, many substances are used by mankind as...
Period: 01.04.2015 - 31.03.2018 Partner: Autodisplay Biotech GmbH, Phytowelt Green Technologies GmbH,...
W. Zhang, B. O. Burek, E. Fernández-Fueyo, M. Alcalde, J. Z. Bloh, F. Hollmann
J. Meyer, A.E.W. Horst, M. Steinhagen, D. Holtmann, M.B. Ansorge-Schumacher, M. Kraume, A. Drews
J. Meyer, D. Holtmann, M. B. Ansorge-Schumacher, M. Kraume, A. Drews
K. D. Belsare, T. Horn, A. J. Ruff, R. Martinez, A. Magnusson, D. Holtmann, J. Schrader, U. Schwaneberg
M. Steinhagen, A. Gräbner, J. Meyer, A. E. W. Horst, A. Drews, D. Holtmann, M. B. Ansorge-Schumacher,