Chapter 37 – Biotechnological Production of Fatty Aldehydes

M. Buchhaupt, F. Kähne, M.M.W. Etschmann, J. Schrader

The α-dioxygenase from rice (Oryza sativa) was cloned into E. coli. Resting cells of this recombinant E. coli strain were able to convert different fatty acids to the respective fatty aldehydes shortened by one carbon atom. Addition of Triton X-100 improved the conversion rate up to 1 g aldehyde per liter per hour. A second biotransformation could be executed without any loss of biocatalytic activity, proving biocatalyst stability.

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