Publikationen und Patente

Patente

2017

2016

2015

2014

2013

2012

2011

2010

S. Zengin Çekiç, D. Holtmann, G. Güven, K.-M. Mangold, U. Schwaneberg, J. Schrader (2010)
Mediated electron transfer with P450cin.Electrochemistry Communications 12 (11) 1547-1550
DOI: 10.1016/j.elecom.2010.08.030

I. Schmidt, H. Schewe, S. Gassel, C. Jin, J. Buckingham, M. Hümbelin, G. Sandmann, J. Schrader (2011)
Biotechnological production of astaxanthin with Phaffia rhodozyma/ Xanthophyllomyces dendrorhous
Appl Microbiol Biotechnol.  89(3):555-71
DOI: 10.1007/s00253-010-2976-6

M. A. Mirata, H. Schewe, D. Holtmann, J. Schrader (2010)
Integrierte Bioproduktion und selektive Aufreinigung von Perillasäure.
Chemie Ingenieur Technik 82 (1-2) 101-109
DOI: 10.1002/cite.200900115

J. Schrader (2010)
Mikrobielle Oxidation von Monoterpenen
BIOspektrum 16 (5) 555-557

M. Buchhaupt, S. Hüttmann, K. Ehrich, J. Schrader (2010)
Überexpression von Chloroperoxidase in Caldariomyces fumago.
Chemie Ingenieur Technik 82 (9) 1528
DOI: 10.1002/cite.201050320

M. Buchhaupt, M.M.W. Etschmann,  J. Schrader (2010)
Green Notes - Natürliche Aromastoffe durch biokatalytische Umwandlung von Fettsäuren.
Chemie Ingenieur Technik 82 (9) 1524
DOI 10.1002/cite.201050434

S. Zengin Çekiç, D. Holtmann, K. M. Mangold, J. Schrader (2010)
Mediated Electron Transfer with P450cin
Chemie Ingenieur Technik 82 (9) 1539
DOI 10.1002/cite.201050738

M.A. Mirata, M. Wüst, A. Mosandl, J. Schrader (2010)
Linalool biotransformation with fungi
In: Expression of Multidisciplinary Flavour Sciene. Proceedings of the 12th Weurman Symposium, July 2008, Interlaken, Switzerland (eds. I. Blank, M. Wüst, C. Yeretzian)
Zürcher Hochschule für Angewandte Wissenschaften 349-353

M.A. Mirata, J. Schrader (2010)
Integrated bioprocess for the production of the natural antimicrobial monoterpene R-(+)-perillic acid with P. putida
In: Expression of Multidisciplinary Flavour Sciene. Proceedings of the 12th Weurman Symposium, July 2008, Interlaken, Switzerland (eds. I. Blank, M. Wüst, C. Yeretzian)
Zürcher Hochschule für Angewandte Wissenschaften 344-348

M.M.W. Etschmann, P. Koetter, W. Bluemke, K.-D. Entian, J. Schrader (2010)
Production of methionol and 3-(methylthio)- propylacetate with yeasts.
In: Expression of Multidisciplinary Flavour Sciene. Proceedings of the 12th Weurman Symposium, July 2008, Interlaken, Switzerland (eds. I. Blank, M. Wüst, C. Yeretzian)
Zürcher Hochschule für Angewandte Wissenschaften 354-357

M.A. Mirata, J. Schrader (2010)
Efficient bioproduction of natural R-(+)-perillic acid.
Bioprocédé haute performance pour la production d'acide périllique naturel.
Proceedings of Cosm'ing 2010 5th International Symposium Cosmetic Ingredients & Biotechnology. 23.-25. June 2010, St. Malo, France. 69-75
ISBN: 978-2-9529879-2-9

2009

M. Etschmann, M. B. Buchhaupt, C. S. W. Studart-Witkowski, W. S. Schwab, J. S. Schrader (2009)
Green notes - natürliche Aromastoffe durch biokatalytische Umwandlung von Fettsäuren Chemie Ingenieur Technik 81 (8) 1307
DOI: 10.1002/cite.200950137

C. Nacke, J. Schrader (2009)
Biokatalytische Aromastoffgewinnung durch regiospezifische Carotinoidspaltung. Chemie Ingenieur Technik 81 (8) 1257
DOI: 10.1002/cite.200950065

C. Nacke, M. Schilling, J. Schrader (2009)
Carotinoid-Biokonversion durch regiospezifische oxidative Spaltung. Chemie Ingenieur Technik 81 (8) 1319-1320
DOI: 10.1002/cite.200950063

S. Zengin Cekic, D. Holtmann, K. M. Mangold, J. Schrader (2009)
Bioelektrokatalyse mit P450 Monooxygenasen - spektroelektrochemische Charakterisierung des mediatorvermittelten Elektronentransfers. Chemie Ingenieur Technik 81 (8) 1318
DOI: 10.1002/cite.200950081

C. Ley, D. Holtmann, K.-M. Mangold, J. Schrader (2009)
Leitfähige Polymere als Immobilisierungsmatrix für Enzyme. Chemie Ingenieur Technik 81 (8) 1318
DOI: 10.1002/cite.200950101

P. Kiefer, M. Buchhaupt, P. Christen, B. Kaup, J. Schrader, J.A. Vorholt (2009)
Metabolite Profiling Uncovers Plasmid-Induced Cobalt Limitation under Methylotrophic Growth Conditions
PLoS One 4 (11): e7831
DOI:10.1371/journal.pone.0007831

C. Nacke, M. Schilling, J. Schrader (2009)
Folding reporter tags can deliver misleading results upon chaperone coexpression
Journal of Biotechnology, 144 (4) 268-271
DOI:10.1016/j.jbiotec.2009.09.012

M.A. Mirata, M. Wüst, J. Schrader (2009)
Stereospecific biotransformations of (R/S)-linalool by Corynespora cassiicola DSM 62475 into linalool oxides.
In: J. Whittall, P.W. Sutton (eds) Practical Methods for Biocatalysis and Biotransformations . John Wiley & Sons.

M. A. Mirata, M. Wüst, A. Mosandl, J. Schrader (2009)
Biotransformation von (+/-)-Linalool mit Pilzen
Chemie Ingenieur Technik 81 (8) 1306-1307
DOI: 10.1002/cite.200950172

B.A. Kaup, U. Piantini, M. Wüst, J. Schrader (2009)
Oxidation and halo-hydroxylation of monoterpenes with choroperoxidase from Leptoxyphium fumago .
In: J. Whittall, P.W. Sutton (eds) Practical Methods for Biocatalysis and Biotransformations . John Wiley & Sons.

M. A. Mirata, D. Heerd, J. Schrader (2009)
Integrated bioprocess for the oxidation of limonene to perillic acid with Pseudomonas putida DSM 12264
Process Biochemistry 44 (7) 764-771
DOI:10.1016/j.procbio.2009.03.013    

M.A. Mirata, J. Schrader (2009)
Improved bioproduction of perillic acid. Benefits of using in situ product removal.
BIOforum Europe (5) 28-29

M. Pescheck, M. A. Mirata, B. Brauer, U. Krings, R. G. Berger, J. Schrader (2009)
Improved monoterpene biotransformation with Penicillium sp. by use of a closed gas loop bioreactor
Journal of Industrial Microbiology and Biotechnology 36 (6) 827-836
DOI:10.1007/s10295-009-0558-3  

F.-C. Huang, G. Horváth, P. Molnár, E. Turcsi, J. Deli , J. Schrader , G. Sandmann , H. Schmidt,  W. Schwab (2009)
Substrate promiscuity of RdCCD1, a carotenoid cleavage oxygenase from Rosa damascena .
Phytochemistry 70 (4) 457-464
DOI:10.1016/j.phytochem.2009.01.020

H. Schewe, D. Holtmann, J Schrader (2009)
P450-BM-3-catalyzed whole-cell biotransformation of α-pinene with recombinant Escherichia coli in an aqueous-organic two-phase system.
Applied Microbiology and Biotechnology 83 (5) 849-857
DOI:10.1007/s00253-009-1917-8

D. Holtmann, K.-M. Mangold, J. Schrader (2009)
Entrapment of cytochrome P450 BM-3 in polypyrrole for electrochemically-driven biocatalysis
Biotechnology Letters 31 (5) 765-770
DOI:10.1007/s10529-009-9925-4

J. Schrader, M. Schilling, D. Holtmann, D. Sell, M. V. Filho, A. Marx, J. A. Vorholt (2009)
Methanol-based industrial biotechnology: current status and future perspectives of methylotrophic bacteria.
Trends in Biotechnology 27 (2): 107-115
DOI:10.1016/j.tibtech.2008.10.009

2008

M. M. W. Etschmann, P. Kötter, J. Hauf, W. Bluemke, K.-D. Entian,  J. Schrader (2008)
Production of the aroma chemicals 3-(methylthio)-1-propanol and 3-(methylthio)-propylacetate with yeasts
Appl Microbiol Biotechnol 80 (4): 579-587
DOI 10.1007/s00253-008-1573-4

H. Schewe, B.-A. Kaup, J. Schrader (2008)
Improvement of P450BM-3 whole-cell biocatalysis by integrating heterologous cofactor regeneration combinind glucose facilitator and dehydrogenase in E. coli.
Appl Microbiol Biotechnol 78 (1): 55-65 
DOI 10.1007/s00253-007-1277-1

M. Schilling, F. Haetzelt, W. Schwab, J. Schrader (2008)
Impact of surfactants on solubilization and activity of the carotenoid cleavage dioxygenase, AtCCD1, in an aqueous micellar reaction system
Biotechnology Letters 30 (4): 701-706
DOI 10.1007/s10529-007-9585-1

B.-A. Kaup, K. Ehrich, M. Pescheck, J. Schrader (2008)
Microparticle-enhanced cultivation of filamentous microorganisms: Increased chloroperoxidase formation by Caldariomyces fumago as an example
Biotechnology and Bioengineering , 99 (3) 491-498
DOI  10.1002/bit.21713

M.A. Mirata, M. Wüst, A. Mosandl, J. Schrader (2008)
Fungal biotransformation of (+/-)-linalool.
J Agric Food Chem. 56 (9):3287-96
DOI: 10.1021/jf800099h

2007

M. Schilling, J. Schrader (2007)
Selective in vitro carotenoid cleavage using a recombinant dioxygenase from Arabidopsis thaliana - AtCCD1 - for the biocatalytic production of β-ionone. In: Hofmann, T., Meyerhof, W. and Schieberle, P. (eds) Recent Highlights in Flavor Chemistry & Biology. Proceedings of the 8th Wartburg Symposium. Deutsche Forschungsanstalt für Lebensmittelchemie, Garching. ISBN 3-9807686-8. 210-215.

H. Schewe, B. Kaup, J. Schrader (2007)
Oxyfunctionalization of α-pinene in a whole-cell bioprocess using recombinant P450 BM-3. Journal of Biotechnology 131 (2): S106-S107

D. Holtmann, K.-M. Mangold, J. Schrader (2007)
Electrochemically driven bio catalysis with P450BM3 entrapped in polypyrrole as conductive polymer. In M. Seliskar and D. Rozman (eds) Cytochromes P450 - Biochemistry, biophysics, functional genomics.  Faculty of Medicine, University of Ljubljana. ISBN 978-961-6264-89-1. 84-85.

D. Holtmann, J. Schrader (2007)
Approaches to Recycling and Substituting NAD(P)H as a CYP Cofactor. In: R.D. Schmid and W. Urlacher (eds) Modern Biooxidation . Enzymes, Reactions and Applications. Wiley, Weinheim. ISBN 978-3-527-31507-9. 265-290.

M. Schilling, F. Patett, W. Schwab, J. Schrader (2007)
Influence of solubility-enhancing fusion proteins and organic solvents on the in vitro biocatalytic performance of the carotenoid cleavage dioxygenase AtCCD1 in a micellar reaction system.
Appl Microbiol Biotechnol  75 (4): 829-836
DOI 10.1007/s00253-007-0878-z

J. Schrader (2007)
Microbial Flavour Production. In: Berger, R.G. (ed) Flavours and Fragrances . Chemistry, Bioprocessing and Sustainability. Springer Berlin Heidelberg. ISBN 978-3-540-49338-9. 507-574.

B.A. Kaup, U. Piantini, M. Wüst, J. Schrader (2007).
Monoterpenes as novel substrates for oxidation and halo-hydroxylation with chloroperoxidase from Caldariomyces fumago .
Appl Microbiol Biotechnol 73 (5): 1087-1096
DOI 10.1007/s00253-006-0559-3

2006

 D. Holtmann, J. Schrader, D. Sell (2006)
Quantitative comparison of the signals of an electrochemical bioactivity sensor during the cultivation of different microorganisms.
Biotechnol Lett  28:889-896
DOI:10.1007/s10529-006-9021-y

F. Patett, M. Schilling, D. Sell, H. Schmidt, W. Schwab, J. Schrader (2006)
Heterologous expression of carotenoid-cleaving dioxygenases from plants for the production of natural flavour compounds
In: W.L.P. Bredie and M.A. Petersen (eds) Developments in Food Science Vol. 43 Flavour Science : Recent Advances and Trends. Elsevier Amsterdam. ISBN 0-444-52742-7. 117-120

M.-A. Mirata, M. Wüst, A. Mosandl, D. Sell, J. Schrader (2006)
Lilac aldehydes and lilac alcohols as metabolic by-products of fungal linalool biotransformation
In: W.L.P. Bredie and M.A. Petersen (eds) Developments in Food Science Vol. 43 Flavour Science : Recent Advances and Trends. Elsevier Amsterdam. ISBN 0-444-52742-7. 121-124

H. Schewe, M. Pescheck, D. Sell, J. Schrader (2006)
Biotechnological production of terpenoid flavour and fragrance compounds in tailored bioprocesses.
In: W.L.P. Bredie and M.A. Petersen (eds) Developments in Food Science Vol. 43 Flavour Science : Recent Advances and Trends. Elsevier Amsterdam. ISBN 0-444-52742-7. 45-48

M.M.W. Etschmann, J. Schrader (2006)
An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast.
Applied Microbiology and Biotechnology   Vol 71 (4) 440-443
DOI: 10.1007/s00253-005-0281-6

P. Gebhart, T. Brinkmann, H. Rubbeling, A. Cordes, D. Sell (2006)
Ökologie und Ökonomie gehen Hand in Hand - Software Sabento bewertet das Nachhaltigkeitspotenzial biotechnologischer Verfahren, in: PROCESS (4) 118 - 119

2005

F. Kocak, K. Vuorilehto,J. Schrader, D. Sell (2005)
Potential-controlled chromatography for the separation of amino acids and peptides
Journal of Applied Electrochemistry , Vol35 (12) 1231-1237.
DOI: 10.1007/s10800-005-9034-6

D. Holtmann (2005)
Elektrochemisches Monitoring mikrobieller Aktivität. Grundlagen und Anwendung in der Abwasserreinigung. Dissertation Universität Magdeburg, Fakultät für Verfahrens- und Systemtechnik.
Abstract  (in German and English)      full text (in German only)

M.M.W. Etschmann, D. Sell, J. Schrader (2005)
Production of 2-phenylethanol and 2-phenylethylacetate from L-phenylalanine by coupling whole-cell biocatalysis with organophilic pervaporation
Biotech Bioeng  Vol 92 (5) 624-634.
DOI 10.1002/bit.20655

M. Pescheck, J. Schrader and D. Sell (2005)
Novel electrochemical sensor system for monitoring metabolic activity during the growth and cultivation of prokaryotic and eukaryotic cells.
Bioelectrochemistry , Vol 67 (1) 47-55.
DOI:10.1016/j.bioelechem.2004.10.004

Rüdiger Kaspera, Ulrich Krings, Michael Pescheck, Dieter Sell, Jens Schrader, and Ralf G. Berger (2005)
Regio- and Stereoselective Fungal Oxyfunctionalisation of Limonenes
Z. Naturforsch. 60c, 459-466.

M.M.W. Etschmann, D. Sell, J. Schrader
"Rose aroma from the bioreactor" - 2-phenylethanol and 2-phenylethyl acetate production with yeasts: Screening, medium optimzation and bioprocess design.
In: Hofmann, T., Rothe, M., Schieberle, P. (eds.) State-of-the-Art in Flavour Chemistry and Biology. Proceedings of the 7th Wartburg Symposium. Deutsche Forschungsanstalt für Lebensmittelchemie 248-253.

2004

S. Schäfer, J. Schrader, D. Sell
Oxygen uptake measurements to monitor the activity of terpene transforming fungi.
Process Biochemistry 39, 2221-2228
DOI:10.1016/j.procbio.2003.11.023

M.M.W. Etschmann
Entwicklung eines integrierten Verfahrens zur biotechnologischen Produktion von 2-Phenylethanol.
Dissertation Universität Münster. Books on Demand GmbH, Norderstedt. ISBN 3-8334-1157-0.

M.M.W. Etschmann, D. Sell, J. Schrader
Medium optimization for the production of the aroma compound 2-phenylethanol using a genetic algorithm.
Journal of Molecular Catalysis B: Enzymatic 29, 187-193.
DOI: 10.1016/j.molcatb.2003.10.014 S1381-1177(04)00056-6

J. Schrader, M.M.W. Etschmann, D. Sell, J.-M. Hilmer, J. Rabenhorst
Applied biocatalysis for the synthesis of natural flavour compounds - current industrial processes and future prospects.
Biotechnology Letters 26 (6) 463-472
DOI:10.1023/B:BILE.0000019576.80594.0e

2003

M. Etschmann, D. Sell, J. Schrader
Microbial production of 2-phenylethanol by an integrated bioprocess
In: Le Quéré, J.L., Étievant, P.X. (eds) Flavour Research at the Dawn of the Twenty-first Century. Proceedings of the 10th Weurman Flavour Research Symposium. Lavoisier Editions Tec & Doc , Paris, 385-388.

A. Biwer, P. Zuber, K. Bellmann, D. Sell, P. Gebhart, E. Heinzle
Ökoeffizienz-Bewertung in der Prozessentwicklung
BioTechnologie transkript Sonderband 2003, 118-121

Gebhart, P.
Weniger Biozide. Hygiene am Beispiel der Reinigung von Flaschenabfüllanlagen in Brauereien. Lebensmitteltechnik 9, 58-60

M.W. Knizia, K. Vuorilehto, J. Schrader, D. Sell
Potential-Controlled Chromatography of Short-Chain Carboxylic Acids
Electroanalysis 15 (1) 49-54
DOI 10.1002/elan.200390004

S. Schäfer, J. Schrader, D. Sell,
Faseroptische Sensoren zum Aktivitätsmonitoring höherer Pilze bei der Terpenbiotransformation
Lebensmittelchemie 57, 121

P. Gebhart
Bilanzierende Betrachtung integrierter Problemlösungen durch biotechnologische Verfahren/Produkte.
In: Brickwedde, F. DBU, Deutsche Bundesstiftung Umwelt (Hrsg.): Biotechnologie - Innovationsmotor einer nachhaltigen Entwicklung / 8. Internationale Sommerakademie St. Marienthal. Berlin : Erich Schmidt, 217-236.

S. Schäfer, R. Kaspera, U. Krings, J. Schrader, D. Sell, R.G. Berger
Sensorgestützte Biokonversion zur Gewinnung natürlicher terpenoider Aromastoffe
Lebensmittelchemie 57, 15

M.M.W. Etschmann, D. Sell, J. Schrader
Screening of yeasts for the production of the aroma compound 2-phenylethanol in a molasses-based medium
Biotechnology Letters 25 (7) 531-536
DOI:10.1023/A:1022890119847

E. Gandert, J. Schrader, D. Sell
Sensorsystem zur Überprüfung der Vergärbarkeit von Mosten und zur Steuerung der alkoholischen Gärung
Chemie Ingenieur Technik 2003, 75, No. 3, 305-309

M. W. Knizia, K. Vuorilehto, J. Schrader, D. Sell
Potential-controlled chromatography of short-chain carboxylic acids
Electroanalysis 1, 49-54

2002

S. Schäfer, J. Schrader, D. Sell
Biokonversion von Terpenkohlenwasserstoffen - Entwicklung einer Aktivitätssensorik für Pilze
Lebensmittelchemie 56, 110

M. Pescheck, J. Schrader, D. Sell
Characterization of starter cultures by determining microbial activity using an electrochemical gel cell.
Food Biotechnology , Vol. 16, Issue 2, 121-134,
DOI: 10.1081/FBT-120014323

D. Holtmann, D. Sell
Detection of the microbial activity of aerobic heterotrophic, anoxic heterotrophic and aerobic autotrophic activated sludge organisms with an electrochemical sensor.
Biotechnology Letters , Vol. 24, Issue 16, 1313-1318

M. M. W. Etschmann, W. Bluemke, D. Sell and J. Schrader
Biotechnological production of 2-phenylethanol.
Applied Microbiology and Biotechnology , Vol 59, No. 1, 1-8
DOI 10.1007/s00253-002-0992-x

D. Holtmann, D. Sell
Electrochemical detection of the microbial activity of heterotrophic and autotrophic activated sludge organisms
Online -Proceedings BioSensor Symposium Tübingen 2001

2001

Biwer, A., Rudershausen, A., Heinzle, E., Bellmann, K., Sell, D., Gebhart, P.
Ökologische und Ökonomische Evaluation biokatalytischer Prozesse während ihrer Entwicklung
in: Heiden, S., Erb, R. (Hrsg.): Biokatalyse, Sonderausgabe der DBU in Kooperation mit BIOspektrum, Spektrum Akademischer Verlag, Heidelberg, S. 15-24

Sell, D., Gebhart, P.
Integrierter Umweltschutz, internationale Wettbewerbsfähigkeit und Standortqualität
in: Heiden, S., Burschel, C., Erb, R. (Hrsg.): Biotechnologie als interdisziplinäre Herausforderung , Spektrum Akademischer Verlag, Heidelberg, Berlin, S. 26-38

D. Holtmann, D. Sell
Sensor Systems for Monitoring Microbial Activity in Industrial Water Circuits. Eng. Life Sci. (1) 6: 233-236

D. Holtmann, D. Sell
Investigations into the application of a process for the determination of microbial activity in biofilms.
Appl Microbiol Biotechnol 56: 826-830
DOI 10.1007/s002530100618

Holtmann, D., Schrader, J., Sell, D., Borchert, A.
Untersuchungen zum bioelektrochemischen Monitoring der Aktivität von Organismen im belebten Schlamm. KA - Wasserwirtschaft, Abwasser, Abfall, (48) 9: 1241-1246

M. Etschmann, P. Gebhart, D.Sell
Economic benefits of the application of biotechnology - Examples. In: Focus on Biotechnology Vol. 4 Engineering and Manufacturing for Biotechnology (Hofman, M., Thonart, P., Eds.), Kluwer Academic Publishers, Dordrecht, 353-360.

D. Sell
Bioelectrochemical Fuel Cells. In: Biotechnology, 2nd Ed., Special Processes (Rehm, H.-J., Reed, G., Pühler, A., Stadler, P., Eds.), Wiley-VCH, Weinheim, New York, 5-23.

Schrader, J., Berger, R.G. (2001)
Biotechnological production of terpenoid flavor and fragrance compounds. In: Biotechnology, 2nd Ed., Special Processes (Rehm, H.-J., Reed, G., Pühler, A., Stadler, P., Eds.), Wiley-VCH, Weinheim, New York, 373-422

Bluemke, W., Schrader, J. (2001)
Integrated bioprocess for enhanced production of natural flavours and fragrances by Ceratocystis moniliformis. Biomolecular Engineering (17), 137-142.

Holtmann, D., Sell, D. (2001)
Sensorsystem zur Überprüfung der mikrobiellen Aktivität in industriellen Wasserkreisläufen. CIT 73 (3), 262-266.

 

 

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